Hexachlorobenzene
Title: Hexachlorobenzene
CAS Registry Number: 118-74-1
Additional Names: Perchlorobenzene
Trademarks: Anticarie; Bunt-cure; Bunt-no-more; Julin's carbon chloride
Molecular Formula: C6Cl6
Molecular Weight: 284.78
Percent Composition: C 25.31%, Cl 74.70%
Literature References: Prepn: Becke, Sperber, US 2792434 (1957 to BASF). Teratogenicity study: K. D. Courtney et al., Toxicol. Appl. Pharmacol. 35, 239 (1976). Carcinogenicity studies: J. R. P. Cabral et al., Nature 269, 510 (1977); D. L. Arnold et al., Food Chem. Toxicol. 23, 779 (1985) (corr. ibid. 26, 169 (1988)). uv spectrum: H. Conrad-Billroth, Z. Phys. Chem. 19, 76 (1932); O. Schnepp, R. Kopelman, J. Chem. Phys. 30, 868 (1959). Toxicology: G. Vettorazzi, Residue Rev. 56, 107 (1975); R. Ockner, R. Schmid, Nature 189, 499 (1961). Review of toxicology and human exposure: Toxicological Profile for Hexachlorobenzene (PB2003-100139, 2002) 403 pp.
Properties: Needles. d23 2.044. mp 231°. bp 323-326°. Vapor pressure at 20°: 1.09 ´ 10-5 mm Hg. Sublimable. Insol in water. Sparingly sol in cold alcohol; sol in benzene, chloroform, ether. Flash point 242°C.
Melting point: mp 231°
Boiling point: bp 323-326°
Flash point: Flash point 242°C
Density: d23 2.044
NOTE: Not to be confused with benzene hexachloride, see Lindane.
CAUTION: Potential symptoms of chronic oral overexposure are dermal lesions, hypertrichosis, anorexia, weight loss, focal alopecia, corneal opacity, atrophic hands, hepatomegaly, porphyria, skeletal muscle wasting. See Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, pp 170-171; Patty's Industrial Hygiene and Toxicology vol. 2B, G. D. Clayton, F. E. Clayton, Eds. (John Wiley & Sons, New York, 4th ed., 1994) pp 1477-1492. This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-138.
Use: In organic syntheses. Formerly as agricultural fungicide.

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