Title: Hexetidine
CAS Registry Number: 141-94-6
CAS Name: 1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-pyrimidinamine
Additional Names: 5-amino-1,3-bis(2-ethylhexyl)hexahydro-5-methylpyrimidine; 1,3-bis(b-ethylhexyl)-5-methyl-5-aminohexahydropyrimidine; 5-amino-1,3-di(b-ethylhexyl)hexahydro-5-methylpyrimidine
Trademarks: Glypesin (Stada); Hexigel (Warner-Lambert); Hexocil (Pharmacia); Hexoral (Pfizer); Hextril (Pfizer); Oraldene (Pfizer); Oraseptic (Warner-Lambert); Sterisil (Warner-Lambert); Steri/Sol (Warner-Lambert)
Molecular Formula: C21H45N3
Molecular Weight: 339.60
Percent Composition: C 74.27%, H 13.36%, N 12.37%
Literature References: Prepn: Senkus, J. Am. Chem. Soc. 68, 1611 (1946); US 2415047; Bell, Necker, US 3054797 (1947, 1962 both to Comm. Solvents Corp.). Comprehensive description: G. Satzinger et al., Anal. Profiles Drug Subs. 7, 277-295 (1978).
Properties: Liquid. d2020 0.8889. bp0.4 160°. nD20 1.4668. Sol in petr ether, methanol, benzene, acetone, ethanol, n-hexane, chloroform. Practically insol in water. pKa 8.3. Has good thermal stability.
Boiling point: bp0.4 160°
pKa: pKa 8.3
Index of refraction: nD20 1.4668
Density: d2020 0.8889
Therap-Cat: Antiseptic.
Therap-Cat-Vet: Antiseptic.
Keywords: Antifungal (Synthetic).

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