Hexobendine
Title: Hexobendine
CAS Registry Number: 54-03-5
CAS Name: 3,4,5-Trimethoxybenzoic acid 1,2-ethanediylbis[(methylimino)-3,1-propanediyl] ester
Additional Names: 3,4,5-trimethoxybenzoic acid diester with 3,3¢-[ethylenebis(methylimino)]di-1-propanol; N,N¢-dimethyl-N,N¢-bis[3-(3¢,4¢,5¢-trimethoxybenzoxy)propyl]ethylenediamine; hexabendin
Molecular Formula: C30H44N2O10
Molecular Weight: 592.68
Percent Composition: C 60.80%, H 7.48%, N 4.73%, O 27.00%
Literature References: Prepn: O. Kraupp, K. Schlögl, AT 231432; eidem, US 3267103 (1964, 1966 both to OSSW). Pharmacology: Rudolph et al., Arzneim.-Forsch. 20, 637 (1970); Kolassa, Pfleger, Biochem. Pharmacol. 20, 490 (1971); H. Rameis et al., Arzneim.-Forsch. 30, 671 (1980).
Properties: mp 75-77°.
Melting point: mp 75-77°
 
Derivative Type: Dihydrochloride
CAS Registry Number: 50-62-4
Manufacturers' Codes: ST-7090
Trademarks: Reoxyl (Byk Gulden); Ustimon; Andiamine (Polfa)
Molecular Formula: C30H44N2O10.2HCl
Molecular Weight: 665.60
Percent Composition: C 54.13%, H 6.97%, N 4.21%, O 24.04%, Cl 10.65%
Properties: Crystals, mp 170-174°. uv max: 267 nm. Freely sol in water, less sol in alc. Practically insol in ether.
Melting point: mp 170-174°
Absorption maximum: uv max: 267 nm
 
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary).

Others monographs:
ParoxetinePrednicarbate1,2-BenzopyranTriphenylmethane
Trypan RedCodeine PhosphateNitrosyl ChlorideSulfachlorpyridazine
Procainamide HydrochlorideBisantrenePolicresulenPropiverine
BufoteninePorphinePropyphenazoneAcepromazine
©2016 DrugLead US FDA&EMEA