HPA-23
Title: HPA-23
CAS Registry Number: 89899-81-0
CAS Name: Hexaoctacontaoxononaantimonateheneicosatungstate(19-) heptadecaammonium disodium
Additional Names: ammonium 5-tungsto-2-antimonate; 5-tungsto-2-antimonate; 21-tungsto-9-antimonate
Molecular Formula: H68Na2N17O86Sb9W21
Molecular Weight: 6685.06
Percent Composition: H 1.03%, Na 0.69%, N 3.56%, O 20.58%, Sb 16.39%, W 57.75%
Line Formula: (NH4)17Na(NaSb9W21O86)
Literature References: One of the condensed mineral heteropolyanions, also called polyoxotungstates. Synthesis: M. Michelon, G. Hervé, C.R. Seances Acad. Sci. Ser. C 274, 209 (1972); M. Michelon et al., J. Inorg. Nucl. Chem. 42, 1583 (1980). Crystal structure: J. Fischer et al., J. Am. Chem. Soc. 98, 3050 (1976). Laser Raman studies of intracellular localization: C. Cibert, C. Jasmin, Biochem. Biophys. Res. Commun. 108, 1424 (1982). Antiviral activity in mice: C. Jasmin et al., J. Natl. Cancer Inst. 53, 469 (1974); G. H. Werner et al., J. Gen. Virol. 31, 59 (1976). In vitro inhibition of rabies virus: H. Tsiang et al., J. Gen. Virol. 40, 665 (1978). Effects in scrapie model systems: R. H. Kimberlin, C. A. Walker, Lancet 2, 591 (1979); eidem, Arch. Virol. 78, 9 (1983). Structure-activity study: M. Hervé et al., Biochem. Biophys. Res. Commun. 116, 222 (1983). Clinical evaluation in AIDS: W. Rozenbaum et al., Lancet 1, 450 (1985); B. L. Moskovitz, Antimicrob. Agents Chemother. 32, 1300 (1988).
Properties: Crystals from water. Solution has pH near 6.7, and is stable around neutrality. LD50 i.p. in mice: 750 mg/kg (Werner).
Toxicity data: LD50 i.p. in mice: 750 mg/kg (Werner)
NOTE: Formerly known as ammonium antimony tungsten oxide.

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