Isoaminile
Title: Isoaminile
CAS Registry Number: 77-51-0
CAS Name: a-[2-(Dimethylamino)propyl]-a-(1-methylethyl)benzeneacetonitrile
Additional Names: 4-(dimethylamino)-2-isopropyl-2-phenylvaleronitrile; 3-cyano-5-dimethylamino-3-phenyl-2-methylhexane; a-(b-dimethylaminopropyl)-a-isopropylphenylacetonitrile
Trademarks: Aprecon; Dimyril; Nullatuss
Molecular Formula: C16H24N2
Molecular Weight: 244.38
Percent Composition: C 78.64%, H 9.90%, N 11.46%
Literature References: Prepn: GB 822695; Stühmer, Funke, US 2934557 (1959, 1960, both to Kali-Chemie).
Properties: Liquid, bp3 138-146°.
Boiling point: bp3 138-146°
 
Derivative Type: Citrate
CAS Registry Number: 28416-66-2
Trademarks: Perocan (Toyo Jozo)
Molecular Formula: C16H24N2.C6H8O7
Molecular Weight: 436.50
Percent Composition: C 60.54%, H 7.39%, N 6.42%, O 25.66%
Properties: Crystals from alcohol + ether, mp 63-64°.
Melting point: mp 63-64°
 
Derivative Type: Cyclamate
CAS Registry Number: 10075-36-2
Trademarks: Mucalan; Peracon (Kali-Chemie)
Molecular Formula: C22H37N3O3S
Molecular Weight: 423.61
Percent Composition: C 62.38%, H 8.80%, N 9.92%, O 11.33%, S 7.57%
Literature References: Prepn: Dickinson, US 3074996 (1963 to Abbott).
 
Derivative Type: Tartrate
Molecular Formula: C16H24N2.C4H6O6
Molecular Weight: 394.46
Percent Composition: C 60.90%, H 7.67%, N 7.10%, O 24.34%
Properties: Crystals, mp 64°.
Melting point: mp 64°
 
Therap-Cat: Antitussive.
Keywords: Antitussive.

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