Laccaic Acid
Title: Laccaic Acid
CAS Name: C.I. Natural Red 25
Additional Names: lac dye; C.I. 75450
Literature References: Pigment found in the lac resin produced by the insect Coccus laccae (Laccifer lacca Kerr) on certain trees in India. Isoln: R. E. Schmidt, Ber. 20, 1285 (1887). Chemistry: O. Dimroth, S. Goldschmidt, Ann. 399, 62 (1913). Originally thought to be one compound, laccaic acid has been separated into four components: A (major), B, C and D. Isoln of A: R. Burwood et al., J. Chem. Soc. C 1965, 6067. Structure of A: eidem, Tetrahedron Lett. 1966, 3059; eidem, J. Chem. Soc. C 1967, 842; E. D. Pandhare et al., Indian J. Chem. 7, 977 (1969). Isoln and structure of B: eidem, Tetrahedron Lett. 1967, 2437; N. S. Bhide et al., Indian J. Chem. 7, 987 (1969); of C: A. V. R. Rao et al., ibid. 188; of D: A. R. Mehandale et al., Tetrahedron Lett. 1968, 2231. Synthesis of D: D. W. Cameron et al., Chem. Commun. 1978, 688; eidem, Aust. J. Chem. 34, 2401 (1981).
 
Derivative Type: Laccaic acid A
Additional Names: Laccaic acid A1
Molecular Formula: C26H19NO12
Molecular Weight: 537.43
Percent Composition: C 58.11%, H 3.56%, N 2.61%, O 35.72%
Properties: Red platelets from methanol, chars at 230°. Absorption max (conc H2SO4): 302, 361, 518, 558 nm (log e 4.33, 4.11, 4.32, 4.37).
Absorption maximum: Absorption max (conc H2SO4): 302, 361, 518, 558 nm (log e 4.33, 4.11, 4.32, 4.37)
 
Derivative Type: Laccaic acid B
Molecular Formula: C24H16O12
Molecular Weight: 496.38
Percent Composition: C 58.07%, H 3.25%, O 38.68%
Properties: Red needles from methanol.
 
Derivative Type: Laccaic acid C
Molecular Formula: C25H17NO13
Molecular Weight: 539.40
Percent Composition: C 55.67%, H 3.18%, N 2.60%, O 38.56%
Properties: Dark red needles from methanol, dec >360°.
 
Derivative Type: Laccaic acid D
Additional Names: Xanthokermesic acid
Molecular Formula: C16H10O7
Molecular Weight: 314.25
Percent Composition: C 61.15%, H 3.21%, O 35.64%
Properties: Yellow needles from water, dec >300°.
 
Use: As crimson dye.

Others monographs:
Molybdenum TrioxideGangliosidesThiazole OrangeGlybuthiazol(e)
CyclorphanSerineHexocyclium Methyl SulfateRelaxin
RoxithromycinPropyl ChlorideLocust Bean GumNeopentane
PolythiazideBradycorEnviomycinMalonic Acid
©2016 DrugLead US FDA&EMEA