Mecloqualone
Title: Mecloqualone
CAS Registry Number: 340-57-8
CAS Name: 3-(2-Chlorophenyl)-2-methyl-4(3H)-quinazolinone
Additional Names: 2-methyl-3-(2-chlorophenyl)-4-quinazolone
Trademarks: Nubarene
Molecular Formula: C15H11ClN2O
Molecular Weight: 270.71
Percent Composition: C 66.55%, H 4.10%, Cl 13.10%, N 10.35%, O 5.91%
Literature References: Prepd from acetylanthranilic acid and o-chloroaniline in the presence of POCl3: Jackman et al., J. Pharm. Pharmacol. 12, 529 (1960); Closa, J. Prakt. Chem. [4] 14, 84 (1961). Metabolism: Dubnick, Towne, Toxicol. Appl. Pharmacol. 22, 82 (1972); Daenens, Van Bovan, Arzneim.-Forsch. 24, 195 (1974).
Properties: Crystals mp 126-128°.
Melting point: mp 126-128°
 
Derivative Type: Hydrochloride
Molecular Formula: C15H11ClN2O.HCl
Molecular Weight: 307.17
Percent Composition: C 58.65%, H 3.94%, Cl 23.08%, N 9.12%, O 5.21%
Properties: Crystals, mp 239-241°.
Melting point: mp 239-241°
 
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.11.
Therap-Cat: Sedative; hypnotic.
Keywords: Sedative/Hypnotic; Quinazolone Derivatives.

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