Title: Methioprim
CAS Registry Number: 588-36-3
CAS Name: 4-Amino-2-methylthio-5-pyrimidinemethanol
Additional Names: 4-amino-2-methylmercapto-5-pyrimidinemethanol; 4-amino-5-hydroxymethyl-2-methylthiopyrimidine
Molecular Formula: C6H9N3OS
Molecular Weight: 171.22
Percent Composition: C 42.09%, H 5.30%, N 24.54%, O 9.34%, S 18.73%
Literature References: Synthesis starting with ethyl ethoxyethylenecyanoacetate: Ulbricht, Price, J. Org. Chem. 21, 567 (1956).
Properties: Needle-like prisms from benzene, mp 126-127°.
Melting point: mp 126-127°
Use: Tumor antagonist in mice.
Status: This monograph has been retired and is no longer subject to revision or update.

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