Methopterin
Title: Methopterin
CAS Registry Number: 2410-93-7
CAS Name: N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Additional Names: N-[4-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]glutamic acid; 10-methylpteroylglutamic acid; N10-methylfolic acid
Molecular Formula: C20H21N7O6
Molecular Weight: 455.42
Percent Composition: C 52.75%, H 4.65%, N 21.53%, O 21.08%
Literature References: Prepn: Cosulich, Smith, J. Am. Chem. Soc. 70, 1922 (1948); Cosulich, US 2563707 (1951 to Am. Cyanamid).
 
Derivative Type: Monohydrate
Properties: Yellow spherulites. uv max (0.1N NaOH): 255, 302, 368 nm (e ´ 10-3 26, 27, 9); (0.1N HCl): 307 nm (e ´ 10-3 25).
Absorption maximum: uv max (0.1N NaOH): 255, 302, 368 nm (e ´ 10-3 26, 27, 9); (0.1N HCl): 307 nm (e ´ 10-3 25)

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