Moxestrol
Title: Moxestrol
CAS Registry Number: 34816-55-2
CAS Name: (11b,17a)-11-Methoxy-19-nor-17-pregna-1,3,5(10)-trien-20-yne-3,17-diol
Additional Names: 3,17-dihydroxy-11b-methoxy-19-nor-17a-pregna-1,3,5-trien-20-yne; 17a-ethynyl-11b-methoxyestra-1,3,5(10)-triene-3,17b-diol; 11b-methoxy-17a-ethynyl-D1,3,5(10)-estratriene-3,17b-diol; 11b-methoxy-17a-ethynylestradiol
Manufacturers' Codes: R-2858
Trademarks: Surestryl (Roussel Diamant)
Molecular Formula: C21H26O3
Molecular Weight: 326.43
Percent Composition: C 77.27%, H 8.03%, O 14.70%
Literature References: Prepn: Bertin, Pierdet, ZA 6703381; eidem, US 3579545; FR M6182, C.A. 72, 90739m (1970) (1968, 1971, 1968 all to Roussel-UCLAF); Azadian-Boulanger, Bertin, Chim. Ther. 8, 451 (1973). Activity studies: Raynaud, Steroids 21, 249 (1973); Raynaud et al., Mol. Pharmacol. 9, 520 (1973).
Properties: Crystals, mp 280°. [a]D20 +29° (c = 0.6 in ethanol). uv max (ethanol): 280 nm (E1%1cm 58.4).
Melting point: mp 280°
Optical Rotation: [a]D20 +29° (c = 0.6 in ethanol)
Absorption maximum: uv max (ethanol): 280 nm (E1%1cm 58.4)
Therap-Cat: Estrogen.
Keywords: Estrogen; Steroidal.

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