Muraglitazar
Title: Muraglitazar
CAS Registry Number: 331741-94-7
CAS Name: N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine
Manufacturers' Codes: BMS-298585
Trademarks: Pargluva (BMS)
Molecular Formula: C29H28N2O7
Molecular Weight: 516.54
Percent Composition: C 67.43%, H 5.46%, N 5.42%, O 21.68%
Literature References: Peroxisome proliferator-activated receptor (PPAR) a/g dual agonist. Prepn: P. T. Cheng, WO 0121602; eidem, US 6414002 (2001, 2002 both to Bristol-Myers Squibb); P. V. Devasthale et al., J. Med. Chem. 48, 2248 (2005). Review of development and therapeutic potential: D. Barlocco, Curr. Opin. Invest. Drugs 6, 427-434 (2005).
Properties: Crystals from ethanol, mp 139.1-140.2°. uv max (methanol): 224, 277 nm.
Melting point: mp 139.1-140.2°
Absorption maximum: uv max (methanol): 224, 277 nm
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic.

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