N-Acetylsulfanilyl Chloride
Title: N-Acetylsulfanilyl Chloride
CAS Registry Number: 121-60-8
CAS Name: 4-(Acetylamino)benzenesulfonyl chloride
Additional Names: p-acetamidobenzenesulfonyl chloride; p-acetaminobenzenesulfonyl chloride; acetanilide-p-sulfonyl chloride; ASC
Molecular Formula: C8H8ClNO3S
Molecular Weight: 233.67
Percent Composition: C 41.12%, H 3.45%, Cl 15.17%, N 5.99%, O 20.54%, S 13.72%
Literature References: Prepd by sulfonation of acetanilide: Stewart, J. Chem. Soc. 121, 2558 (1922); Smiles, Stewart, Org. Synth. coll. vol. I, 8 (2nd ed., 1941).
Properties: Thick, light tan prisms from benzene, mp 149°. Has slight odor of acetic acid. Benzene and ether are poor solvents for purification by recrystn. Much better results are obtained using chloroform or ethylene dichloride. Cf. Northey, Sulfonamides (New York, 1948) p 12.
Melting point: mp 149°
CAUTION: Irritant to skin, eyes, and mucous membranes of nose and throat.
Use: Intermediate in the prepn of sulfanilamide and its derivs.

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