N-Methyl-N'-nitro-N-nitrosoguanidine
Title: N-Methyl-N¢-nitro-N-nitrosoguanidine
CAS Registry Number: 70-25-7
Additional Names: N-Methyl-N-nitroso-N¢-nitroguanidine; MNNG
Molecular Formula: C2H5N5O3
Molecular Weight: 147.09
Percent Composition: C 16.33%, H 3.43%, N 47.61%, O 32.63%
Literature References: Prepn: A. F. McKay, G. F. Wright, J. Am. Chem. Soc. 69, 3028 (1947). Reviews of carcinogenicity and mutagenicity studies: IARC Monographs 4, 183-195 (1974); U. Sinha, B. B. Chattoo, J. Sci. Ind. Res. 3, 499-505 (1975).
Properties: Yellow crystals from methanol, mp 118° (dec). Reacts with aq KOH to form diazomethane: A. F. McKay, J. Am. Chem. Soc. 70, 1974 (1948). Reacts at acid pH to give methylnitroguanidine.
Melting point: mp 118° (dec)
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-172.
Use: Exptlly as carcinogen and mutagen. Formerly in prepn of diazomethane.

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