Nealbarbital
Title: Nealbarbital
CAS Registry Number: 561-83-1
CAS Name: 5-(2,2-Dimethylpropyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Additional Names: 5-allyl-5-neopentylbarbituric acid; nealbarbitone; neallymal
Trademarks: Nevental (Pharmacia); Censedal (M & B)
Molecular Formula: C12H18N2O3
Molecular Weight: 238.28
Percent Composition: C 60.49%, H 7.61%, N 11.76%, O 20.14%
Literature References: Synthesis: Brandstrom, Acta Chem. Scand. 13, 613, 615, 619 (1959); GB 797017 and US 2899435 (1958, 1959, both to Pharmacia). Metabolism: J. N. T. Gilbert et al., J. Pharm. Pharmacol. 26, 119 (1974); J. N. T. Gilbert, J. W. Powell, Eur. J. Drug Metab. Pharmacokinet. 3, 195 (1978).
Properties: Slightly bitter crystals, mp 155-157°. Practically insol in water, petr ether. Moderately sol in chloroform; freely sol in alcohol, ether, acetone. Also sol in aq alkaline solns.
Melting point: mp 155-157°
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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