Nicomorphine
Title: Nicomorphine
CAS Registry Number: 639-48-5
CAS Name: (5a,6a)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol di-3-pyridinecarboxylate (ester)
Additional Names: morphine ester with nicotinic acid; morphine bis(nicotinate); morphine bis(pyridine-3-carboxylate); nicotinic acid morphine ester; morphine dinicotinate
Trademarks: Gewalan (Lannacher); Vilan (Lannacher)
Molecular Formula: C29H25N3O5
Molecular Weight: 495.53
Percent Composition: C 70.29%, H 5.09%, N 8.48%, O 16.14%
Literature References: Prepn: Pongratz, Zirm, Monatsh. Chem. 88, 330 (1957); GB 807115 (1959 to Lannacher Heilmittel).
Properties: Crystals, mp 178-178.5° (corr.). Practically insol in water. Sol in ethanol.
Melting point: mp 178-178.5° (corr.)
 
Derivative Type: Hydrochloride
Molecular Formula: C29H25N3O5.HCl
Molecular Weight: 531.99
Percent Composition: C 65.47%, H 4.93%, N 7.90%, O 15.04%, Cl 6.66%
Properties: Dec 248°. Sol in water with neutral reaction.
 
NOTE: This is a controlled substance (opium derivative): 21 CFR, 1308.11.
Therap-Cat: Analgesic (narcotic).
Keywords: Analgesic (Narcotic).

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