Nifenazone
Title: Nifenazone
CAS Registry Number: 2139-47-1
CAS Name: N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide
Additional Names: N-antipyrinylnicotinamide; 2,3-dimethyl-1-phenyl-4-(3-pyridinecarboxamido)-5-pyrazolone; 2,3-dimethyl-4-nicotinamido-1-phenyl-5-pyrazolone; 4-nicotinamido-1,5-dimethyl-2-phenyl-3-pyrazolone; 4-(N-nicotinoylamino)-1-phenyl-2,3-dimethyl-5-pyrazolone; N-nicotinoylaminoantipyrine
Trademarks: Dolongan (S.M.B.); Nicopyron (Trommsdorff); Nikofezon; Niprazina (Italfarmaco); Phenicazone; Reupiron; Thylin
Molecular Formula: C17H16N4O2
Molecular Weight: 308.33
Percent Composition: C 66.22%, H 5.23%, N 18.17%, O 10.38%
Literature References: Prepn: Heid, DE 897407 (1953); Trommsdorff, BE 635597 (1963); Pongraz, Zirm, Monatsh. Chem. 88, 330 (1957); Zorn, Schmidt, Pharmazie 12, 396 (1957).
Properties: Crystals from alc, mp 252-253° (also reported as mp 256-258°). Sparingly sol in water, acetone, ethyl acetate, ether; sol in hot water, alcohol, chloroform, dil acids.
Melting point: mp 252-253° (also reported as mp 256-258°)
Therap-Cat: Analgesic, antipyretic.
Keywords: Analgesic (Non-Narcotic); Antipyretic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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