Norcodeine
Title: Norcodeine
CAS Registry Number: 467-15-2
CAS Name: (5a,6a)-7,8-Didehydro-4,5-epoxy-3-methoxymorphinan-6-ol
Additional Names: N-desmethylcodeine; normorphine 3-methyl ether
Molecular Formula: C17H19NO3
Molecular Weight: 285.34
Percent Composition: C 71.56%, H 6.71%, N 4.91%, O 16.82%
Literature References: Prepn from acetylcodeine: von Braun, Ber. 47, 2312 (1914); DE 286743 (1914); Chem. Zentralbl. 1915, II, 862; Frdl. 12, 741; Houben 4, 588; cf. DE 289273 (1914); from codeine N-oxide: Diels, Fischer, Ber. 49, 1723 (1916); from codeine: Speyer, Walther, Ber. 63, 822 (1930).
Properties: Plates or needles from acetone or ethyl acetate, mp 185°. Sparingly sol in water, ether. Moderately sol in acetone. Freely sol in hot methanol, ethanol.
Melting point: mp 185°
 
Derivative Type: Hydrochloride trihydrate
Molecular Formula: C17H19NO3.HCl.3H2O
Molecular Weight: 375.84
Percent Composition: C 54.33%, H 6.97%, N 3.73%, O 25.54%, Cl 9.43%
Properties: Needles from water. When anhydr, dec 309°. Sparingly sol in cold water, more sol in hot water. Freely sol in methanol, ethanol. Almost insol in acetone.
 
Derivative Type: Sulfate
Molecular Formula: 2C17H19NO3.H2SO4
Molecular Weight: 668.75
Percent Composition: C 61.06%, H 6.03%, N 4.19%, O 23.92%, S 4.79%
Properties: Crystals, freely sol in water.
 
Derivative Type: Acetate (salt)
Molecular Formula: C17H19NO3.C2H4O2
Molecular Weight: 345.39
Percent Composition: C 66.07%, H 6.71%, N 4.06%, O 23.16%
Properties: Crystals, freely sol in water.

Others monographs:
VirginiamycinMethenamine Allyl IodideProgesteroneChalcomycin
PindoneHyperforinAmylene DichloridePhenyl Aminosalicylate
FennelClorexolonem-PhenylenediamineGlyoxal-Sodium Bisulfite
2,4,6-Trichloro-m-cresolBenfluralinEtryptamineOil of Chenopodium
©2016 DrugLead US FDA&EMEA