Norethynodrel
Title: Norethynodrel
CAS Registry Number: 68-23-5
CAS Name: (17a)-17-Hydroxy-19-norpregn-5(10)-en-20-yn-3-one
Additional Names: 17a-ethynyl-17-hydroxy-5(10)-estren-3-one; 13-methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15H-cyclopenta[a]phenanthren-3-one
Molecular Formula: C20H26O2
Molecular Weight: 298.42
Percent Composition: C 80.50%, H 8.78%, O 10.72%
Literature References: Prepn: Colton, US 2691028, US 2725389 (1954, 1955 to Searle). Metabolism studies in mice: Freudenthal et al., Toxicol. Appl. Pharmacol. 24, 125 (1973).
Properties: Crystals from aq methanol, mp 169-170°. [a]D +108° (1% chloroform).
Melting point: mp 169-170°
Optical Rotation: [a]D +108° (1% chloroform)
 
Derivative Type: Mixture with mestranol
CAS Registry Number: 8015-30-3
Trademarks: Conovid E (Searle); Enavid (Searle); Enovid
 
Therap-Cat: Progestogen. In combination with estrogen as contraceptive (oral).
Keywords: Contraceptive (Oral); Progestogen.

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