o-Nitrophenol
Title: o-Nitrophenol
CAS Registry Number: 88-75-5
Additional Names: 2-Nitrophenol
Molecular Formula: C6H5NO3
Molecular Weight: 139.11
Percent Composition: C 51.80%, H 3.62%, N 10.07%, O 34.50%
Literature References: Prepd by the nitration of phenol; separated by steam distillation. Review of toxicology and human exposure: Toxicological Profile for Nitrophenols: 2-Nitrophenol and 4-Nitrophenol (PB93-110823, 1992) 131 pp.
Properties: Light yellow needles or prisms; peculiar, aromatic odor. d 1.495. mp 44-45°. bp 214-216°. Volatile with steam. Slightly sol in cold water, freely in hot water, in alcohol, benzene, ether, carbon disulfide, alkali hydroxides. LD50 orally in mice, rats: 1.297, 2.828 g/kg, K. C. Back et al., Reclassification of Materials Listed as Transportation Health Hazards (TSA-20-72-3; PB214-270, 1972).
Melting point: mp 44-45°
Boiling point: bp 214-216°
Density: d 1.495
Toxicity data: LD50 orally in mice, rats: 1.297, 2.828 g/kg, K. C. Back et al., Reclassification of Materials Listed as Transportation Health Hazards (TSA-20-72-3; PB214-270, 1972)
Use: Manuf dyes, paint colorings, rubber chemicals, and fungicides. Indicator in 2% alc soln. pH: 5.0 colorless, 7.0 yellow, but the color change is not sharp and cannot be used where CO2 is present; as reagent for glucose.

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