Opipramol
Title: Opipramol
CAS Registry Number: 315-72-0
CAS Name: 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol
Additional Names: 5-[g-[4-(b-hydroxyethyl)piperazino]propyl]dibenzo[b,f]azepine; N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene; 4-[3-(5H-dibenzo[b,f]azepin-5-yl)propyl]-1-(2-hydroxyethyl)piperazine
Molecular Formula: C23H29N3O
Molecular Weight: 363.50
Percent Composition: C 76.00%, H 8.04%, N 11.56%, O 4.40%
Literature References: Prepn: FR M209 (1961 to Rhône-Poulenc), C.A. 58, 3442f (1963); Schindler, DE 1133729; CH 359143; CH 360061 (all 1962 to Geigy), C.A. 58, 10219a, 10218f, 10218h (1963).
Properties: Crystals, mp 100-101°.
Melting point: mp 100-101°
 
Derivative Type: Dihydrochloride
CAS Registry Number: 909-39-7
Trademarks: Dinsidon (Novartis); Ensidon (Novartis); Insidon (Novartis)
Molecular Formula: C23H29N3O.2HCl
Molecular Weight: 436.42
Percent Composition: C 63.30%, H 7.16%, N 9.63%, O 3.67%, Cl 16.25%
Properties: Crystals from ethanol, mp 210° (FR M209); mp 228-230° (DE 1133729). Sol in water, alcohol; sparingly sol in acetone.
Melting point: mp 210° (FR M209); mp 228-230° (DE 1133729)
 
Therap-Cat: Antidepressant; antipsychotic.
Keywords: Antidepressant; Tricyclics; Antipsychotic; Other Tricyclics.

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