Oxiniacic Acid
Title: Oxiniacic Acid
CAS Registry Number: 2398-81-4
CAS Name: 3-Pyridinecarboxylic acid 1-oxide
Additional Names: nicotinic acid 1-oxide; 3-carboxypyridine N-oxide
Molecular Formula: C6H5NO3
Molecular Weight: 139.11
Percent Composition: C 51.80%, H 3.62%, N 10.07%, O 34.50%
Literature References: Prepn: Clemo, Koenig, J. Chem. Soc. 1949, S231; Taylor, Crovetti, J. Org. Chem. 19, 1633 (1954). Mass spectrum: Bild, Hesse, Helv. Chim. Acta 50, 1885 (1967). Therapeutic effect: Debay, Thery, BE 618968 (1962), C.A. 58, 12375e (1963).
Properties: Needles, mp 254-255° (dec). Slightly soluble in cold water, more sol in hot water, hot glacial acetic acid, hot methanol, less sol in ethanol. Insol in light petroleum, benzene, chloroform. uv max (0.1N H2SO4): 220, 260 nm (e 22400, 10200).
Melting point: mp 254-255° (dec)
Absorption maximum: uv max (0.1N H2SO4): 220, 260 nm (e 22400, 10200)
Derivative Type: Ethanolamine salt
CAS Registry Number: 36296-31-8
Additional Names: Ethanolamine oxiniacate
Trademarks: Novacyl (Astra)
Molecular Formula: C6H5NO3.C2H7NO
Molecular Weight: 200.19
Percent Composition: C 48.00%, H 6.04%, N 13.99%, O 31.97%
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Nicotinic Acid Derivatives.

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