Pargyline
Title: Pargyline
CAS Registry Number: 555-57-7
CAS Name: N-Methyl-N-2-propynylbenzenemethanamine
Additional Names: N-methyl-N-2-propynylbenzylamine; N-benzyl-N-methyl-2-propynylamine; N-methyl-N-propargylbenzylamine
Manufacturers' Codes: MO-911; A-19120
Trademarks: Eudatin (Abbott); Supirdyl
Molecular Formula: C11H13N
Molecular Weight: 159.23
Percent Composition: C 82.97%, H 8.23%, N 8.80%
Literature References: Monoamine oxidase inhibitor. Prepd from propargyl bromide and benzylmethylamine: GB 906245; Martin, US 3155584 (1962 and 1964, both to Abbott). Activity as a glucuronyl transferase inducer: Yeh, Mitchell, Experientia 28, 298 (1972).
Properties: Free base, bp11 96-97°.
Boiling point: bp11 96-97°
 
Derivative Type: Hydrochloride
CAS Registry Number: 306-07-0
Trademarks: Eutonyl (Abbott)
Molecular Formula: C11H13N.HCl
Molecular Weight: 195.69
Percent Composition: C 67.51%, H 7.21%, N 7.16%, Cl 18.12%
Properties: Crystals from ethanol + ether, mp 154-155°. Readily sol in water. Aq solns are unstable.
Melting point: mp 154-155°
 
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Monoamine Oxidase Inhibitor.

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