Pearlman's Catalyst
Title: Pearlman's Catalyst
CAS Registry Number: 12135-22-7
CAS Name: Palladium hydroxide (Pd(OH)2)
Additional Names: palladium hydroxide on carbon
Molecular Formula: H2O2Pd
Molecular Weight: 140.43
Percent Composition: H 1.44%, O 22.79%, Pd 75.78%
Line Formula: Pd(OH)2/C
Literature References: Commercial product contains 20 wt % Pd(OH)2 on carbon. Prepn: W. M. Pearlman, Tetrahedron Lett. 8, 1663 (1967); and catalytic activity study: R. J. Card et al., J. Catal. 79, 13 (1983). Catalytic applications in debenzylating amines: R. C. Bernotas, R. V. Cube, Synth. Commun. 20, 1209 (1990); in Nef-type reactions: T. Capecchi et al., J. Chem. Soc. Perkin Trans. 1 2000, 2681; in Pd-catalyzed coupling reactions: Y. Mori, M. Seki, J. Org. Chem. 68, 1571 (2003); in oxidation of silyl enol ethers: J.-Q. Yu et al., Org. Lett. 7, 1415 (2005).
Use: Nonpyrophoric catalyst for hydrogenolysis of benzyl-nitrogen and benzyl-oxygen bonds.

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