Penicillin G Benzhydrylamine
Title: Penicillin G Benzhydrylamine
CAS Registry Number: 1538-11-0
CAS Name: [2S-(2a,5a,6b)]-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compd with a-phenylbenzenemethanamine (1:1)
Additional Names: 1,1-diphenylmethylamine benzylpenicillinate; benzylpenicillin benzhydrylamine; benzhydrylamine penicillin; penicillin aminodiphenylmethane salt; benzylpenicillinic acid benzhydrylamine salt
Molecular Formula: C29H31N3O4S
Molecular Weight: 517.64
Percent Composition: C 67.29%, H 6.04%, N 8.12%, O 12.36%, S 6.19%
Line Formula: C16H18N2O4S.C13H13N
Literature References: Semi-synthetic antibiotic. Prepd from potassium penicillin G and benzhydrylamine HCl in dil acetone: Hagemann et al., Ann. Pharm. Fr. 12, 565 (1954); Goldsmith et al., Antibiot. Chemother. 5, 648 (1955); Penau, Hagemann, US 2710863 (1955 to Labs. Français de Chimiothérapie).
Properties: Crystals from dil acetone, mp 159°. [a]D20 +206° (c = 1). Soly in water at 24°: 0.7%. Insol in vegetable oils.
Melting point: mp 159°
Optical Rotation: [a]D20 +206° (c = 1)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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