Pfeiffer's Substance
Title: Pfeiffer's Substance
CAS Registry Number: 8015-18-7
CAS Name: 5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione mixture with 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
Additional Names: 4-(Dimethylamino)antipyrine compd with 5,5-diethylbarbituric acid (1:1); corps de Pfeiffer
Molecular Formula: C21H29N5O4
Molecular Weight: 415.49
Percent Composition: C 60.71%, H 7.04%, N 16.86%, O 15.40%
Literature References: A molecular compd of aminopyrine and barbital, prepd by repeated crystn of stoichiometric amounts of the components from a minimum of hot water: Pfeiffer, Z. Physiol. Chem. 146, 98 (1925).
Properties: Silky needles, mp 113-115°. At 115° the melt is turbid, but turns into a clear liquid at 140°. Freely sol in water. The aminopyrine moiety dissolves in benzene, while the barbital moiety precipitates out.
Melting point: mp 113-115°

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