Phenallymal
Title: Phenallymal
CAS Registry Number: 115-43-5
CAS Name: 5-Phenyl-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Additional Names: 5-allyl-5-phenylbarbituric acid; 5-phenyl-5-allylbarbituric acid; phenallymalum; alphenal; prophenal
Trademarks: Alphenate; Allofenyl; Fenallymal
Molecular Formula: C13H12N2O3
Molecular Weight: 244.25
Percent Composition: C 63.93%, H 4.95%, N 11.47%, O 19.65%
Literature References: Its methods of prepn are similar to those used for phenobarbital: Slotta, Grundriss der modernen Arzneistoff-Synthese (Stuttgart, 1931) p 45. Metabolism: D. J. Harvey et al., Res. Commun. Chem. Pathol. Pharmacol. 4, 247 (1972); eidem, Drug Metab. Dispos. 5, 527 (1977).
Properties: Crystals, mp 156-157.5°. Bitter taste. Readily sol in alcohol, chloroform. One gram dissolves in 580 ml water, in 10 ml ether, in 500 ml benzene, in 4000 ml carbon tetrachloride, in 17,500 ml petr ether.
Melting point: mp 156-157.5°
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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