Phenmetrazine
Title: Phenmetrazine
CAS Registry Number: 134-49-6
CAS Name: 3-Methyl-2-phenylmorpholine
Additional Names: 3-methyl-2-phenyltetrahydro-2H-1,4-oxazine; 2-phenyl-3-methyltetrahydro-1,4-oxazine
Manufacturers' Codes: A-66
Molecular Formula: C11H15NO
Molecular Weight: 177.24
Percent Composition: C 74.54%, H 8.53%, N 7.90%, O 9.03%
Literature References: Prepn: Thomae, Wick, US 2835669 (1958 to Boehringer, Ing.); Siemer, Hengen, US 3018222 (1962 to Ravensberg Chem.); Clark, J. Org. Chem. 27, 3251 (1962); Klosa, J. Prakt. Chem. 21, 12 (1963).
Properties: Liquid. bp12 138-140°; bp1 104°.
Boiling point: bp12 138-140°; bp1 104°
 
Derivative Type: Hydrochloride
CAS Registry Number: 1707-14-8
Trademarks: Marsin (Ikapharm); Neo-Zine (Neo); Preludin (Boehringer, Ing.)
Molecular Formula: C11H15NO.HCl
Molecular Weight: 213.70
Percent Composition: C 61.82%, H 7.55%, N 6.55%, O 7.49%, Cl 16.59%
Properties: Crystals from ethanol + ether, mp 182°. One gram dissolves in 0.4 ml water, in 2.0 ml 95% alc, in 2.0 ml chloroform. Sparingly sol in ether.
Melting point: mp 182°
 
NOTE: This is a controlled substance (stimulant): 21 CFR, 1308.12.
Therap-Cat: Anorexic.
Keywords: Anorexic; CNS Stimulant.

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