Phenprocoumon
Title: Phenprocoumon
CAS Registry Number: 435-97-2
CAS Name: 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one
Additional Names: 3-(a-ethylbenzyl)-4-hydroxycoumarin; 3-(1-phenylpropyl)-4-hydroxycoumarin
Trademarks: Falithrom (Hexal); Marcoumar (Roche); Marcumar (Roche); Liquamar (Organon)
Molecular Formula: C18H16O3
Molecular Weight: 280.32
Percent Composition: C 77.12%, H 5.75%, O 17.12%
Literature References: Prepn: Grüssner, Balthasar, US 2723276 (1955 to Hoffmann-La Roche); Junek, Ziegler, Monatsh. Chem. 87, 218 (1956); Schroeder, Link, J. Am. Chem. Soc. 79, 3291 (1957); US 2872457 (1959 to Wisconsin Alumni Res. Found.); GB 805748 (1958 to Geigy); L. R. Pohl, J. Med. Chem. 18, 513 (1975). Resolution: Preis et al., US 3239529 (1966 to Wisconsin Alumni Res. Found.). Conformation in soln: E. J. Valente et al., J. Med. Chem. 21, 141, 231 (1978).
Properties: Crystals or prisms from dil methanol, mp 179-180°.
Melting point: mp 179-180°
Therap-Cat: Anticoagulant.
Keywords: Anticoagulant.

Others monographs:
Nitroakridin 3582Lasalocid AStarch, SolubleChicle
sec-Octyl BromideBarium PermanganateAbrineChlorphenesin Carbamate
EthohexadiolUndecoylium ChlorideAmmonium CaprylateRuthenium Trichloride
MedrogestoneImazosulfuronCholecystokininTriphenylene
©2016 DrugLead US FDA&EMEA