Phenylpropylmethylamine
Title: Phenylpropylmethylamine
CAS Registry Number: 93-88-9
CAS Name: N,b-Dimethylbenzeneethanamine
Additional Names: dl-N,b-dimethylphenethylamine; dl-N-methyl-2-phenylpropylamine; 1-methylamino-2-phenylpropane; phenpromethamine; 1-methylamino-2-methyl-2-phenylethane
Trademarks: Vonedrine
Molecular Formula: C10H15N
Molecular Weight: 149.23
Percent Composition: C 80.48%, H 10.13%, N 9.39%
Literature References: Synthesis starting with the condensation of chlorobenzene with allyl chloride, followed by ammonolysis: Patrick et al., J. Am. Chem. Soc. 68, 1009 (1946).
Properties: Volatile liquid. d425 0.915-0.925; bp760 205-210°; bp15 95-96°; nD20 1.5102. Slightly sol in water (1.2 g/100 ml). Freely sol in alcohol, ether, benzene. Aq solns are strongly alkaline; pH of a soln of 2 drops (~0.1 ml) dil with 10 ml H2O is ~10.5.
Boiling point: bp760 205-210°; bp15 95-96°
Index of refraction: nD20 1.5102
Density: d425 0.915-0.925
 
Derivative Type: Hydrochloride
Molecular Formula: C10H15N.HCl
Molecular Weight: 185.69
Percent Composition: C 64.68%, H 8.68%, N 7.54%, Cl 19.09%
Properties: mp 144-148°.
Melting point: mp 144-148°
 
Therap-Cat: Adrenergic.
Keywords: a-Adrenergic Agonist; Decongestant.

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