Piketoprofen
Title: Piketoprofen
CAS Registry Number: 60576-13-8
CAS Name: 3-Benzoyl-a-methyl-N-(4-methyl-2-pyridinyl)benzeneacetamide
Additional Names: m-benzoyl-N-(4-methyl-2-pyridyl)hydratropamide; 2-(3-benzoylphenyl)-N-(4-methyl-2-pyridyl)propionamide
Trademarks: Calmatel (aerosol) (Almirall-Omega)
Molecular Formula: C22H20N2O2
Molecular Weight: 344.41
Percent Composition: C 76.72%, H 5.85%, N 8.13%, O 9.29%
Literature References: Derivative of ketoprofen, q.v. used topically as cream or aerosol. Prepn: R. G. W. Spickett et al., GB 1436502 (1976 to Antonio Gallardo, S.A.). Pharmacology and clinical efficacy: E. Tarrus et al., 2nd Eur. Congr. Biopharm. Pharmacokinet. 1, 483 (1984).
Properties: Oil, sol in methylene chloride, ethanol. Insol in water.
 
Derivative Type: Hydrochloride
CAS Registry Number: 59512-37-7
Trademarks: Calmatel (cream) (Almirall-Omega)
Molecular Formula: C22H20N2O2.HCl
Molecular Weight: 380.87
Percent Composition: C 69.38%, H 5.56%, N 7.36%, O 8.40%, Cl 9.31%
Properties: mp 180-182°.
Melting point: mp 180-182°
 
Therap-Cat: Anti-inflammatory (topical).
Keywords: Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives.

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