Pivcefalexin
Title: Pivcefalexin
CAS Registry Number: 63836-75-9
CAS Name: (6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
Additional Names: 7-(D-2-amino-2-phenylacetamido)desacetoxycephalosporanic acid pivaloyloxymethyl ester; pivcephalexin
Molecular Formula: C22H27N3O6S
Molecular Weight: 461.53
Percent Composition: C 57.25%, H 5.90%, N 9.10%, O 20.80%, S 6.95%
Literature References: Orally active semi-synthetic cephalosporin antibiotic; deriv of cephalexin, q.v. Prepn: W. O. Godtfredsen, E. T. Binderup, DE 1951012 (1970 to Lövens Kemiske Fabrik), C.A. 72, 132761v (1970). Pharmacology: P. Foresta et al., Arzneim.-Forsch. 27, 819 (1977). Absorption and excretion: E. Trabucchi et al., Clin. Ther. 81, 299 (1977). Clinical trial: C. Vittorini et al., Arzneim.-Forsch. 31, 1163 (1981).
 
Derivative Type: Hydrochloride
CAS Registry Number: 27726-31-4
Manufacturers' Codes: ST-21
Trademarks: Ausocef (Ausonia); Bencef (Fargal-Pharmasint); Cefalen (Lenza); Cefalex (Von Boch); Pivacef (Firma); Sigmacef (Sigma Tau)
Molecular Formula: C22H27N3O6S.HCl
Molecular Weight: 497.99
Percent Composition: C 53.06%, H 5.67%, N 8.44%, O 19.28%, S 6.44%, Cl 7.12%
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.

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