Procainamide Hydrochloride
Title: Procainamide Hydrochloride
CAS Registry Number: 614-39-1
CAS Name: 4-Amino-N-[2-(diethylamino)ethyl]benzamide monohydrochloride
Additional Names: procaine amide hydrochloride
Trademarks: Amisalin (Daiichi); Novocamid (Hoechst); Procamide (Sintesa); Procanbid (Parke-Davis); Procan-SR (Parke-Davis); Procapan (Panray); Pronestyl (BMS)
Molecular Formula: C13H22ClN3O
Molecular Weight: 271.79
Percent Composition: C 57.45%, H 8.16%, Cl 13.04%, N 15.46%, O 5.89%
Literature References: Prepn: M. Yamazaki et al., J. Pharm. Soc. Jpn. 73, 294 (1953); Y. Tashika, M. Kuranari, ibid. 1069. Comprehensive description: R. B. Poet, H. Kadin, Anal. Profiles Drug Subs. 4, 333-383 (1975).
Properties: Crystals, mp 165-169°. uv max: 278 nm. Freely sol in water. Sol in alc; slightly sol in chloroform; very sparingly sol in benzene, ether. The pH of a 10% aq soln is 5.5.
Melting point: mp 165-169°
Absorption maximum: uv max: 278 nm
Therap-Cat: Antiarrhythmic (class IA).
Keywords: Antiarrhythmic.

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