Procodazole
Title: Procodazole
CAS Registry Number: 23249-97-0
CAS Name: 1H-Benzimidazole-2-propanoic acid
Additional Names: b-(2-benzimidazolyl)propionic acid; 2-(2-carboxyethyl)benzimidazole; propazol
Manufacturers' Codes: AL-1241
Trademarks: Estimulocel (Alonga)
Molecular Formula: C10H10N2O2
Molecular Weight: 190.20
Percent Composition: C 63.15%, H 5.30%, N 14.73%, O 16.82%
Literature References: Non-specific, active immunoprotective agent against viral and bacterial infections. Prepn: J. Maier, Ann. 327, 17 (1903); R. Meyers, H. Lüders, ibid. 415, 29 (1918); B. Chatterjee, J. Chem. Soc. 1929, 2966; ES 407882 (1972 to Lafarquim). Pharmacological studies: C. Fernández et al., Rev. Clin. Esp. 135, 539 (1974); eidem, ibid. 141, 51 (1976). Clinical studies: M. Pérez Tascon, J. M. Monturio, Med. Klin. 181, 78 (1976).
Properties: Silky white needles from water, mp 228° (dec). Sol in alc, warm water. Practically insol in ether, benzene. The water soln is extremely sweet-tasting.
Melting point: mp 228° (dec)
Therap-Cat: Immunopotentiator (non-specific).
Keywords: Immunomodulator.

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