Profenofos
Title: Profenofos
CAS Registry Number: 41198-08-7
CAS Name: O-(4-Bromo-2-chlorophenyl)phosphorothioic acid O-ethyl S-propyl ester
Manufacturers' Codes: CGA-15324; OMS-2004
Trademarks: Curacron (Syngenta); Sanofos (Sanonda); Selecron (Syngenta)
Molecular Formula: C11H15BrClO3PS
Molecular Weight: 373.63
Percent Composition: C 35.36%, H 4.05%, Br 21.39%, Cl 9.49%, O 12.85%, P 8.29%, S 8.58%
Literature References: Organophosphorus insecticide for use in cotton and vegetables. Prepn: E. Beriger, J. Drabek, BE 789937; eidem, US 3992533 (1973, 1976 both to Ciba-Geigy). Resolution and biological activity of chiral isomers: H. Leader, J. E. Casida, J. Agric. Food Chem. 30, 546 (1982). Persistence and biochemical effects of residue in potatoes: R. A. Habiba et al., ibid. 40, 1852 (1992); in tomatoes: S. M. M. Ismail et al., ibid. 41, 610 (1993). Effect on microbial flora of soil: A. Y. Abdel-Mallek et al., Microbiol. Res. 149, 167 (1994). Toxicity to eastern rainbow fish: A Kumar, J. C. Chapman, Environ. Toxicol. Chem. 17, 1799 (1998). Review of physical properties and field trials: F. Buholzer, Proc. 8th Br. Insectic. Fungic. Conf. 1975, 659-665.
Properties: Slightly yellowish liquid. bp0.001 110°. d20 1.455 g/cc. Soly in water at 20°: 20 ppm. Misc with methanol, dichloromethane, benzene, hexane. Vapor pressure at 20°: ~10-5 mm Hg. n20D 1.5466. LD50 in rat (mg/kg): 358-400 orally; ~3300 dermally; LC50 (4 hr) in rat (mg/m3): ~3000 by inhalation (Buholzer). LC50 (96 hr) in rainbow fish: 0.91 mg/l (Kumar, Chapman).
Boiling point: bp0.001 110°
Index of refraction: n20D 1.5466
Density: d20 1.455
Toxicity data: LD50 in rat (mg/kg): 358-400 orally; ~3300 dermally; LC50 (4 hr) in rat (mg/m3): ~3000 by inhalation (Buholzer); LC50 (96 hr) in rainbow fish: 0.91 mg/l (Kumar, Chapman).
Use: Insecticide; acaricide.

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