Pseudocumene
Title: Pseudocumene
CAS Registry Number: 95-63-6
CAS Name: 1,2,4-Trimethylbenzene
Additional Names: pseudocumol; asymmetrical trimethylbenzene
Molecular Formula: C9H12
Molecular Weight: 120.19
Percent Composition: C 89.94%, H 10.06%
Literature References: Occurs in coal tar and in many petroleums. Physical properties: Hirschler, Falconer, J. Am. Chem. Soc. 68, 210 (1946). Metabolism study: J. Huo et al., Xenobiotica 19, 161 (1989). GC/MS determn in serum: E. Kenndler et al., J. Anal. Toxicol. 13, 211 (1989). Neurotoxic effects of inhalation exposure: Z. Korsak, K. Rydzynski, Int. J. Occup. Med. Environ. Health 9, 341 (1996). Genotoxicity study: E. Janik-Spiechowicz et al., Mutat. Res. 412, 299 (1998).
Properties: Liquid. d420 0.8761. bp 169-171°. mp -43.78° (Hirschler, Falconer). nD21 1.5044. Practically insol in water. Sol in alc, benzene, ether. Oxidation yields trimellitic anhydride. LD50 i.p. in male, female mice (mg/kg): 5000, 4100 (Janik-Spiechowicz).
Melting point: mp -43.78° (Hirschler, Falconer)
Boiling point: bp 169-171°
Index of refraction: nD21 1.5044
Density: d420 0.8761
Toxicity data: LD50 i.p. in male, female mice (mg/kg): 5000, 4100 (Janik-Spiechowicz)
CAUTION: Potential symptoms of overexposure are irritation of eyes, skin, nose, throat, respiratory system; bronchitis; hypochromic anemia; headache, drowsiness, fatigue, dizziness, nausea, incoordination; vomiting, confusion; aspiration of liquid may cause chemical pneumonia. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 320.
Use: Sterilizing catgut by heating one hour at 160°; solvent in manuf dyes, perfumes and resins. Solvent for liquid scintillation counting solns.

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