Puberulonic Acid
Title: Puberulonic Acid
CAS Registry Number: 82-83-7
CAS Name: 5,6,7-Trihydroxy-1H-cyclohepta[c]furan-1,3,4-trione
Additional Names: 4,5,6-trihydroxy-7-oxo-1,3,5-cycloheptatriene-1,2-dicarboxylic anhydride
Molecular Formula: C9H4O7
Molecular Weight: 224.12
Percent Composition: C 48.23%, H 1.80%, O 49.97%
Literature References: Antibiotic substance produced by Penicillium puberulum, P. aurantiovirens, P. johannioli, P. cyclopium viridicatum. Isoln: Birkinshaw, Raistrick, Biochem. J. 26, 441 (1932); Barger, Dorrer, ibid. 28, 11 (1934). Structure: McGowan, Chem. Ind. (London) 1947, 205; Aulin-Erdtman, Acta Chem. Scand. 4, 1325 (1950). Johnson et al., J. Chem. Soc. 1951, 1139. Synthesis: Nozoe et al., Bull. Chem. Soc. Jpn. 33, 1071 (1960). Biosynthesis: Ferritti, Richards, Proc. Natl. Acad. Sci. USA 46, 1438 (1960); A. I. Scott, E. Lee, Chem. Commun. 1972, 655. Review: Nozoe, Fortschr. Chem. Org. Naturst. 13, 232-301 (1956).
Properties: Yellow plates, dec 296°. Sol in water. The yellow color of an aq soln changes to pink on neutralization and disappears altogether when the soln is made alkaline.
 
Derivative Type: Sodium salt
Properties: Crystals from ethanol, freely sol in water.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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