Salicylanilide
Title: Salicylanilide
CAS Registry Number: 87-17-2
CAS Name: 2-Hydroxy-N-phenylbenzamide
Additional Names: N-phenylsalicylamide
Trademarks: Salinidol (Doak)
Molecular Formula: C13H11NO2
Molecular Weight: 213.23
Percent Composition: C 73.23%, H 5.20%, N 6.57%, O 15.01%
Literature References: Usually made by the reaction of salicylic acid with aniline in the presence of PCl3 at an elevated temp. Better yields are obtained by using an inert organic solvent such as toluene or carbon tetrachloride as a reaction diluent. Novel process using ion-exchange resins: Majewski, Skelly, US 3221051 (1965). Alternate process: Majewski et al., US 3231611 (1966 to Dow).
Properties: Odorless leaflets. mp 135.8-136.2°. Slightly sol in water; freely sol in alcohol, ether, chloroform, benzene.
Melting point: mp 135.8-136.2°
CAUTION: In concd form may cause irritation of skin, mucous membranes. See also Salicylic Acid.
Use: Anti-mildew, fungicide.
Therap-Cat: Antifungal (topical).
Therap-Cat-Vet: Antifungal (topical).
Keywords: Antifungal (Synthetic).

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