Sarpagine
Title: Sarpagine
CAS Registry Number: 482-68-8
CAS Name: Sarpagan-10,17-diol
Additional Names: raupine
Molecular Formula: C19H22N2O2
Molecular Weight: 310.39
Percent Composition: C 73.52%, H 7.14%, N 9.03%, O 10.31%
Literature References: Isoln from Rauwolfia serpentina (L.) Benth., Apocynaceae: Stoll, Hofmann, Helv. Chim. Acta 36, 1143 (1953). Structure: Stauffacher et al., ibid. 40, 508 (1957); Poisson et al., Bull. Soc. Chim. Fr. 1957, 610; Biemann, J. Am. Chem. Soc. 83, 4801 (1961). Stereochemistry: Bartlett et al., ibid. 84, 622 (1962); Ohashi et al., Tetrahedron 19, 2241 (1963).
Properties: Needles from methanol or ethanol, long plates from acetone, dec >320°. [a]D20 +54° (c = 0.5 in pyridine). uv max (ethanol): 230, 278 nm (log e 4.30, 3.92). One gram dissolves in 60 ml boiling ethanol, 250 ml boiling methanol, 400 ml boiling acetone. Practically insol in chloroform.
Optical Rotation: [a]D20 +54° (c = 0.5 in pyridine)
Absorption maximum: uv max (ethanol): 230, 278 nm (log e 4.30, 3.92)
 
Derivative Type: Hydrochloride
Molecular Formula: C19H22N2O2.HCl
Molecular Weight: 346.85
Percent Composition: C 65.79%, H 6.68%, N 8.08%, O 9.23%, Cl 10.22%
Properties: Needles from alcohol, dec >220°.

Others monographs:
Apocynum cannabinumAmphetamineα-Ribazoleα-Phenylglycine
ThiaclopridPrednylideneSteproninSAICAR
SulfadimethoxineSoapCyanogen AzideBromelain
XyloseArsenic TrifluorideApafantHydrogen Selenide
©2016 DrugLead US FDA&EMEA