Skimmianine
Title: Skimmianine
CAS Registry Number: 83-95-4
CAS Name: 4,7,8-Trimethoxyfuro[2,3-b]quinoline
Additional Names: b-fagarine; 7,8-dimethoxydictamnine
Molecular Formula: C14H13NO4
Molecular Weight: 259.26
Percent Composition: C 64.86%, H 5.05%, N 5.40%, O 24.68%
Literature References: In Skimmia japonica Thunb., Fagara spp., Glycosmis pentaphylla Corr., Ruta graveolens L., Rutaceae: Honda, Arch. Exp. Pathol. Pharmakol. 52, 83 (1904); Paris, Moyse-Mignon, Ann. Pharm. Fr. 5, 410 (1947), C.A. 42, 3909h (1948); Chatterjee, Majumdar, J. Am. Chem. Soc. 76, 2459 (1954); Schneider, Arzneim.-Forsch. 14, 435 (1964). Identity with b-fagarine: Deulofeu et al., J. Am. Chem. Soc. 64, 2326 (1942). Structure: Asahina, Inubuse, Ber. 63, 2052 (1930).
Properties: Pyramids, octahedral rods from alcohol. mp 178°. uv max (ethanol): 212, 251, 321, 331 nm (log e 4.10, 4.91, 3.89, 3.91). Neutral to litmus. Sol in alcohol, chloroform; slightly in ether, amyl alcohol and carbon disulfide; practically insol in water and petr ether.
Melting point: mp 178°
Absorption maximum: uv max (ethanol): 212, 251, 321, 331 nm (log e 4.10, 4.91, 3.89, 3.91)

Others monographs:
Methylergonovine1,1-DiphenyletheneAngostura BarkTamarind
ConhydrineConivaptanPerfluorohexaneCalcium Propionate
BuprofezinTreprostinilMethenamine SalicylateToluene-3,4-dithiol
Thiamine TriphosphateAmmonium NitroferricyanideMethadoneVitamin(s) L
©2016 DrugLead US FDA&EMEA