Sodium Iodomethamate
Title: Sodium Iodomethamate
CAS Registry Number: 519-26-6
CAS Name: 1,4-Dihydro-3,5-diiodo-1-methyl-4-oxo-2,6-pyridinedicarboxylic acid disodium salt
Additional Names: 3,5-diiodo-1-methylchelidamic acid sodium salt; disodium N-methyl-3,5-diiodo-4-pyridone-2,6-dicarboxylate; iodoxyl
Manufacturers' Codes: D-40
Trademarks: Neo-Iopax (Schering); Pyelectan; Uropac (M & B)
Molecular Formula: C8H3I2NNa2O5
Molecular Weight: 492.90
Percent Composition: C 19.49%, H 0.61%, I 51.49%, N 2.84%, Na 9.33%, O 16.23%
Literature References: Prepn: Chelidonic acid is converted to chelidamic acid by the action of NH3, chelidamic acid is iodinated with iodine in a boiling aq alkaline soln, the iodinated product is methylated at the nitrogen with dimethyl sulfate in hot alkaline soln, cf. Dohrn, Diedrich, Ann. 494, 284 (1932); DE 545916; DE 545266; DE 556142; US 1919417 (1933).
Properties: Crystals, dec around 200° with effervescence. Freely sol in water (1:1). Practically insol in chloroform, ether, acetone, petr ether.
Therap-Cat: Diagnostic aid (radiopaque medium).
Keywords: Diagnostic Aid (Radiopaque Medium).

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