Sulfathiourea
Title: Sulfathiourea
CAS Registry Number: 515-49-1
CAS Name: 4-Amino-N-(aminothioxomethyl)benzenesulfonamide
Additional Names: 1-sulfanilyl-2-thiourea; sulfathiocarbamide
Manufacturers' Codes: RP-2255
Trademarks: Badional; Fontamide
Molecular Formula: C7H9N3O2S2
Molecular Weight: 231.30
Percent Composition: C 36.35%, H 3.92%, N 18.17%, O 13.83%, S 27.73%
Literature References: Prepd by reacting acetylsulfanilylcyanamide with hydrogen sulfide. Has also been prepd directly from sulfanilyl cyanamide and ammonium sulfide: Leitch et al., Can. J. Res. 23B, 139 (1945); alternate method: Földi et al., US 2332906 (1943).
Properties: Crystals, dec 171.5-172°. Soly in water at 37°: 1.1 g/100 ml.
 
Derivative Type: Sodium salt
CAS Registry Number: 6101-34-4
Molecular Formula: C7H8N3NaO2S
Molecular Weight: 221.21
Percent Composition: C 38.01%, H 3.65%, N 19.00%, Na 10.39%, O 14.47%, S 14.50%
Properties: Dec 245-245.5°. Very sol in water. pH of 1% aq soln: 7.
 
Derivative Type: Water sol form
Trademarks: Solufontamide
Properties: Marketed as a slightly viscous soln contg 33% of 1-sulfanilyl-2-thiourea. d415 1.16. pH 6.8-7.2.
Density: d415 1.16
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfonamides.

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