Suloctidil
Title: Suloctidil
CAS Registry Number: 54063-56-8
CAS Name: 4-[(1-Methylethyl)thio]-a-[1-(octylamino)ethyl]benzenemethanol
Additional Names: erythro-p-(isopropylthio)-a-[1-(octylamino)ethyl]benzyl alcohol; 1-(4-isopropylthiophenyl)-2-octylaminopropanol
Manufacturers' Codes: CP-556S; MJF-12637
Trademarks: Bemperil (Sidus); Cerebro (Sidus); Circleton (IBI); Dulasi (Dukron); Duloctil (Searle); Euvasal (Synthelabo); Fluversin (Searle); Fluvisco (Searle); Hemoantin (Lepetit); Iangene (Farmochim. Ital.); Loctidon (Lepetit); Locton (Lepetit); Octamet (Belphar); Polivasal (Coli); Sudil (Caber); Sulocton (Continental Pharma); Sulodene (Alfa)
Molecular Formula: C20H35NOS
Molecular Weight: 337.56
Percent Composition: C 71.16%, H 10.45%, N 4.15%, O 4.74%, S 9.50%
Literature References: Prepn: G. Lambelin et al., DE 2334404 (1974 to Continental Pharma), C.A. 82, 97820w (1975). Pharmacology: R. Roncucci et al., Naturwissenschaften 62, 141 (1975); J. Roba et al., Eur. J. Pharmacol. 37, 265 (1976); eidem, Arch. Int. Pharmacodyn. 221, 54 (1976); T. Godfraind, ibid. 342.
Properties: Crystals from n-pentane or methanol-water, mp 62-63°. LD50 orally in mice: 3700 mg/kg (Lambelin).
Melting point: mp 62-63°
Toxicity data: LD50 orally in mice: 3700 mg/kg (Lambelin)
Therap-Cat: Vasodilator (peripheral).
Keywords: Vasodilator (Peripheral).
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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