Sulprostone
Title: Sulprostone
CAS Registry Number: 60325-46-4
CAS Name: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-butenyl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
Manufacturers' Codes: CP-34089; SHB-286; ZK-57671
Trademarks: Nalador (Schering AG)
Molecular Formula: C23H31NO7S
Molecular Weight: 465.56
Percent Composition: C 59.34%, H 6.71%, N 3.01%, O 24.06%, S 6.89%
Literature References: Analog of prostaglandin E2, q.v., with uterine stimulant activity. Prepn: J. Bindra, M. R. Johnson, DE 2355540 (1974 to Pfizer), C.A. 81, 49330u (1974); eidem, US 4024179 (1977 to Pfizer). Antifertility effects: H. Hess et al., Experientia 33, 1076 (1977). Influence on platelet function: R. C. Briel, T. H. Lippert, Adv. Prostaglandin Thromboxane Res. 6, 351 (1980). Biological action and half-life: eidem, Prostaglandins Med. 6, 1 (1981). Induction of abortion: K. Schmidt-Gollwitzer, Int. J. Fertil. 26, 86 (1981).
Properties: Colorless oil.
Therap-Cat: Abortifacient.
Keywords: Abortifacient/Interceptive; Prostaglandin/Prostaglandin Analog.

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