Tetraethylammonium Chloride
Title: Tetraethylammonium Chloride
CAS Registry Number: 56-34-8
CAS Name: N,N,N-Triethylethanaminium chloride
Additional Names: etamon chloride; TEA chloride
Molecular Formula: C8H20ClN
Molecular Weight: 165.70
Percent Composition: C 57.99%, H 12.17%, Cl 21.40%, N 8.45%
Line Formula: N(C2H5)4Cl
Literature References: Potassium-selective ion channel blocker. Prepn: H. Schiff, U. Monsacchi, Z. Phys. Chem. 24, 513 (1897). Synthetic applications: G. Coppens et al., J. Org. Chem. 27, 3299 (1962); S. Gervat et al., Tetrahedron Lett. 34, 2115 (1993). Hydrogen bonding structural studies: K. M. Harmon, J. M. Gabriele, Inorg. Chem. 20, 4013 (1981); idem et al., J. Mol. Struct. 216, 53 (1990). Toxicity studies: J. F. Keith, Jr. et al., Circulation 6, 902 (1952). Mechanistic study of selective potassium channel binding: W. Jarolimek et al., Mol. Pharmacol. 49, 165 (1996).
Properties: Deliquescent crystals. d421 1.0801. Freely sol in water, alcohol, chloroform, acetone; slightly sol in benzene. pH of 10% aq soln 6.48. LD50 i.v. in dogs: 55.7-72.4 mg/kg (Keith, Jr.).
Density: d421 1.0801
Toxicity data: LD50 i.v. in dogs: 55.7-72.4 mg/kg (Keith, Jr.)
 
Derivative Type: Tetrahydrate
CAS Registry Number: 6024-76-6
Properties: Monoclinic prismatic crystals. mp 37.5°. d 1.084.
Melting point: mp 37.5°
Density: d 1.084
 
Use: Dehydrogenation catalyst; phase transfer catalyst in polymerization reactions. Electrolyte in membrane transport studies.

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