Thenaldine
Title: Thenaldine
CAS Registry Number: 86-12-4
CAS Name: 1-Methyl-N-phenyl-N-(2-thienylmethyl)-4-piperidinamine
Additional Names: 1-methyl-4-N-2-thenylanilinopiperidine; 1-methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine; thenophenopiperidine; 1-methyl-4-[phenyl-(2-thenyl)amino]piperidine; thenalidine
Trademarks: Sandostene (Sandoz)
Molecular Formula: C17H22N2S
Molecular Weight: 286.43
Percent Composition: C 71.29%, H 7.74%, N 9.78%, S 11.19%
Literature References: Prepn: Stoll, Bourquin, US 2717251 and US 2757175 (1955 and 1956 to Sandoz).
Properties: bp0.02 158-160°, mp 95-97°.
Melting point: mp 95-97°
Boiling point: bp0.02 158-160°
 
Derivative Type: Tartrate
Properties: Crystals, mp 170-172°.
Melting point: mp 170-172°
 
Therap-Cat: Tartrate as antihistaminic; antipruritic.
Keywords: Antihistaminic; Alkylamine Derivatives; Antipruritic.

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