Tretoquinol
Title: Tretoquinol
CAS Registry Number: 21650-42-0
CAS Name: 1,2,3,4-Tetrahydro-1-[(3,4,5-trimethoxyphenyl)methyl]-6,7-isoquinolinediol
Additional Names: 1-(3¢,4¢,5¢-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; trimethoquinol
Molecular Formula: C19H23NO5
Molecular Weight: 345.39
Percent Composition: C 66.07%, H 6.71%, N 4.06%, O 23.16%
Literature References: Synthesis of dl-form: Yamato et al., Tetrahedron Suppl. 8, 129 (1966). Pharmacology: Fogelman, Grundy, Br. J. Pharmacol. 38, 416 (1970). Metabolic studies: Meshi et al., Biochem. Pharmacol. 19, 2937 (1970); Satoh et al., Chem. Pharm. Bull. 19, 667 (1971).
 
Derivative Type: dl-Form hydrochloride
CAS Registry Number: 18559-63-2
Properties: Pale yellow crystals from methanol + ether, decomp 224.5-226°.
 
Derivative Type: l-Form hydrochloride
CAS Registry Number: 18559-59-6
Manufacturers' Codes: AQ-110
Trademarks: Inolin (Tanabe Seiyaku); Vems (Searle)
Molecular Formula: C19H23NO5.HCl
Molecular Weight: 381.85
Percent Composition: C 59.76%, H 6.34%, N 3.67%, O 20.95%, Cl 9.28%
Properties: Pale yellow crystals, freely sol in water; sol in alcohol.
 
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator.

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