Triethylamine
Title: Triethylamine
CAS Registry Number: 121-44-8
CAS Name: N,N-Diethylethanamine
Molecular Formula: C6H15N
Molecular Weight: 101.19
Percent Composition: C 71.22%, H 14.94%, N 13.84%
Line Formula: (C2H5)3N
Literature References: Prepd by reaction of N,N-diethylacetamide with lithium aluminum hydride: Uffer, Schlittler, Helv. Chim. Acta 31, 1397 (1948). Manuf by vapor phase alkylation of ammonia with ethanol: Lemon, Myerly, US 3022349 (1962 to Union Carbide). Toxicity study: H. F. Smyth et al., Arch. Ind. Hyg. Occup. Med. 4, 119 (1951).
Properties: Liquid; strong ammoniacal odor; d425 0.7255; mp -115°; bp 89-90°; nD20 1.4003. Flash pt, closed cup: 20°F (-6°C). Slightly sol in water above 18.7°; misc with alcohol, ether, also with water below 18.7°. Keep well closed. LD50 orally in rats: 0.46 g/kg (Smyth).
Melting point: mp -115°
Boiling point: bp 89-90°
Flash point: Flash pt, closed cup: 20°F (-6°C)
Index of refraction: nD20 1.4003
Density: d425 0.7255
Toxicity data: LD50 orally in rats: 0.46 g/kg (Smyth)
 
Derivative Type: Hydrochloride
Molecular Formula: C6H15N.HCl
Molecular Weight: 137.65
Percent Composition: C 52.35%, H 11.72%, N 10.18%, Cl 25.76%
Properties: Crystals from alcohol, mp 253-254°, sublimes at 245°; d 1.069. Sol in 0.7 parts water; sol in alcohol, chloroform; very slightly sol in benzene. Practically insol in ether.
Melting point: mp 253-254°
Density: d 1.069
 
CAUTION: Potential symptoms of overexposure to triethylamine are irritation of eyes, respiratory system and skin. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 318.
Use: In the prepn of quaternary ammonium compds.

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