Trifluomeprazine
Title: Trifluomeprazine
CAS Registry Number: 2622-37-9
CAS Name: N,N,b-Trimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine
Additional Names: 10-[3-(dimethylamino)-2-methylpropyl]-2-(trifluoromethyl)phenothiazine
Manufacturers' Codes: RP-7746
Molecular Formula: C19H21F3N2S
Molecular Weight: 366.44
Percent Composition: C 62.28%, H 5.78%, F 15.55%, N 7.64%, S 8.75%
Literature References: Prepn: GB 813861 corresp to G. E. Ullyot, US 2921069 (1959, 1962 both to SK&F). Metabolism study: T. L. Flanagan et al., J. Pharm. Sci. 51, 996 (1962). Chromatographic studies: M. W. Anders, G. J. Mannering, J. Chromatogr. 7, 258 (1962); R. J. Warren et al., J. Pharm. Sci. 55, 144 (1966); B. B. Wheals, J. Chromatogr. 187, 65 (1980). Pharmacological studies: R. C. Kelsey, G. J. Frishmuth, Arch. Int. Pharmacodyn. Ther. 173, 44 (1968); E. W. Baur, J. Pharmacol. Exp. Ther. 177, 219 (1971).
Properties: uv max (95% ethanol): 308, 258 nm (log e 3.60, 4.55).
Absorption maximum: uv max (95% ethanol): 308, 258 nm (log e 3.60, 4.55)
 
Derivative Type: Maleate
Trademarks: Nortran (Norden)
Molecular Formula: C19H21F3N2S.C4H4O4
Molecular Weight: 482.52
Percent Composition: C 57.25%, H 5.22%, F 11.81%, N 5.81%, S 6.65%, O 13.26%
 
Therap-Cat-Vet: Tranquilizer.

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