Trimecaine
Title: Trimecaine
CAS Registry Number: 616-68-2
CAS Name: 2-Diethylamino-2¢,4¢,6¢-trimethylacetanilide
Additional Names: N-sym-trimethylphenyldiethylaminoacetamide; 2-diethylaminoacetyl-2¢,4¢,6¢-trimethylanilide
Manufacturers' Codes: S-203
Trademarks: Mesocaine; Mesidicaine; Mesokain
Molecular Formula: C15H24N2O
Molecular Weight: 248.36
Percent Composition: C 72.54%, H 9.74%, N 11.28%, O 6.44%
Literature References: Prepn: Löfgren, Lundqvist, US 2441498 (1948 to Astra); A. Borovansky et al., J. Am. Pharm. Assoc. 48, 402 (1959).
Properties: Crystals, mp 44°. bp6 187°; bp0.6 154-155°. LD50 s.c. in mice: 295 mg/kg (Borovansky).
Melting point: mp 44°
Boiling point: bp6 187°; bp0.6 154-155°
Toxicity data: LD50 s.c. in mice: 295 mg/kg (Borovansky)
 
Derivative Type: Hydrochloride
Molecular Formula: C15H24N2O.HCl
Molecular Weight: 284.82
Percent Composition: C 63.25%, H 8.85%, N 9.84%, O 5.62%, Cl 12.45%
Properties: Crystals from acetone, mp 140°.
Melting point: mp 140°
 
Therap-Cat: Anesthetic.
Keywords: Anesthetic (Local).

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