Vitamin K5
Title: Vitamin K5
CAS Registry Number: 83-70-5
CAS Name: 4-Amino-2-methyl-1-naphthalenol
Additional Names: 4-amino-2-methyl-1-naphthol; 2-methyl-4-amino-1-hydroxynaphthalene; 3-methyl-4-hydroxy-1-naphthylamine
Trademarks: Synkamin (Parke-Davis)
Molecular Formula: C11H11NO
Molecular Weight: 173.21
Percent Composition: C 76.28%, H 6.40%, N 8.09%, O 9.24%
Literature References: Prepn: Sah, Rec. Trav. Chim. 59, 458 (1940); 60, 373 (1941); Veldstra, Wiardi, ibid. 61, 547 (1942); 62, 75 (1943). Insulin-mimicking effect on glucose transport: J. N. Livingston et al., Am. J. Physiol. 234, E484 (1978). Polargraphic determn in aq soln: K. Takamura, F. Watanabe, Methods Enzymol. 67, 134 (1980).
 
Derivative Type: Hydrochloride
CAS Registry Number: 130-24-5
Molecular Formula: C11H11NO.HCl
Molecular Weight: 209.67
Percent Composition: C 63.01%, H 5.77%, N 6.68%, O 7.63%, Cl 16.91%
Properties: Needles from dil HCl, darkens at 262°, dec 280-282°. Turns pink to dark violet on exposure to air and light. Freely sol in water; slightly sol in alc. Insol in ether.
 
Use: Chemical probe to study insulin-activated hexose transport.
Therap-Cat: Vitamin (prothrombogenic).
Keywords: Vitamin/Vitamin Source; Vitamin K.

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